HBV associated nephrotic syndrome: resolution with oral lamivudine.
نویسندگان
چکیده
A 6 year old boy presenting with a five month history of fever, lethargy, and anorexia, was found to have hepatitis B associated membranous glomerulonephropathy and nephrotic syndrome. After two months treatment with oral lamivudine, his proteinuria cleared and serum albumin and aminotransferases normalised, associated with disappearance of hepatitis B e antigen (HBeAg) and appearance of anti-HBeAg antibodies. After 12 months, without side effects, lamivudine was discontinued. He remains well 11 months off treatment.
منابع مشابه
Case Report Successful Treatment of Hepatitis B Virus Associated Nephrotic Syndrome With Oral Lamivudine in a Nigerian Child: A Case Report
Hepatitis B virus is a well described cause of nephrotic syndrome (NS) worldwide, the typical lesion being membranous glomerulonephropathy. HBV associated NS has been successfully treated with intravenous alpha interferon (IFN), an anti-viral agent. In recent times there have been reports of treatment with lamivudine, an orally administered nucleoside analogue inhibitor of HBV DNA polymerase in...
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عنوان ژورنال:
- Archives of disease in childhood
دوره 88 5 شماره
صفحات -
تاریخ انتشار 2003